Medications are not candies: use of glucocorticoids for chronic diseases

Authors

DOI:

https://doi.org/10.30973/inventio/2023.19.48/6

Keywords:

glucocorticoids, medicines, anti-inflammatory, self-medication, pharmacology

Abstract

Glucocorticoids have become one of the key drugs during the pharmacological treatment of inflammatory chronic diseases. However, despite its undoubted benefit, its prolonged and unsupervised use can generate a series of adverse effects, ranging from mild to severe. In moments of crisis, such as the COVID-19 pandemic, it shows us that practices so widespread in our country such as self-medication and the use of miracle products can put the health of the general population at risk.

Author Biographies

  • Adriana Alejandra Moctezuma Ocampo, Doctorado en Farmacia, Facultad de Farmacia (FF), Universidad Autónoma del Estado de Morelos (UAEM)

    Doctorado en Farmacia, Facultad de Farmacia (FF), Universidad Autónoma del Estado de Morelos (UAEM)

  • José Luis Montiel Hernández, Facultad de Farmacia (FF), Universidad Autónoma del Estado de Morelos (UAEM)

    Facultad de Farmacia (FF), Universidad Autónoma del Estado de Morelos (UAEM)

References

Adcock, I. M. y Mumby, S. (2017). Glucocorticoids. Handb Exp Pharmacol, 237, 171-196. http://doi.org/10.1007/164_2016_98

Alessi, J., de Oliveira, G. B., Schaan, B. D. y Telo, G. H. (2020). Dexamethasone in the era of COVID-19: friend or foe? An essay on the effects of dexamethasone and the potential risks of its inadvertent use in patients with diabetes. Diabetol Metab Syndr, 12, 80. https://doi.org/10.1186/s13098-020-00583-7

Alten, R. y Wiebe, E. (2015). Hypothalamic-pituitary-adrenal axis function in patients with rheumatoid arthritis treated with different glucocorticoid approaches. Neuroimmunomodulation, 22(1-2), 83-88. http://doi.org/10.1159/000362731

Baracaldo-Santamaria, D., Trujillo-Moreno, M. J., Perez-Acosta, A. M., Feliciano-Alfonso, J. E., Calderon-Ospina, C. A. y Soler, F. (2022). Definition of self-medication: a scoping review. Ther Adv Drug Saf, 13, 20420986221127501. http://doi.org/10.1177/20420986221127501

Buttgereit, F., da Silva, J. A., Boers, M., Burmester, G. R., Cutolo, M., Jacobs, J., Kirwan, J., Köhler, L., van Riel, P., Visher, T. y Bijlsma, J. W. (2002). Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology. Ann Rheum Dis, 61(8), 718-722. http://doi.org/10.1136/ard.61.8.718

Cain, D. W. y Cidlowski, J. A. (2017). Immune regulation by glucocorticoids. Nat Rev Immunol, 17(4), 233-247. http://doi.org/10.1038/nri.2017.1

Comisión Federal para la Protección de Riesgos Sanitarios (2021a). Alerta sanitaria de suplementos alimenticios. Gobierno de México, COFEPRIS. https://www.gob.mx/cms/uploads/attachment/file/247147/Alerta_Sanitaria_GLUCOAJO_C2_09082017.pdf

Comisión Federal para la Protección de Riesgos Sanitarios (2021b). Alerta sobre comercialización ilegal del producto “Artri Ajo King”. Gobierno de México/COFEPRIS. https://www.gob.mx/cofepris/articulos/cofepris-alerta-sobre-comercializacion-ilegal-del-producto-artri-ajo-king-el-cual-no-cuenta-con-registro-sanitario?idiom=es

Coutinho, A. E. y Chapman, K. E. (2011). The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol, 335(1), 2-13. http://doi.org/10.1016/j.mce.2010.04.005

Dickmeis, T. (2009). Glucocorticoids and the circadian clock. J Endocrinol, 200(1), 3-22. http://doi.org/10.1677/JOE-08-0415

Fu, J., Cuppen, B. V., Welsing, P. M., van Wietmarschen, H., Harms, A. C., Berger, R., Koval, S., Fritsch-Stork, R. D. E., Bijlsma, J. W. J., Hankemeier, T., van der Greef, J. y Lafeber, F. P. J. G. (2016). Differences between serum polar lipid profiles of male and female rheumatoid arthritis patients in response to glucocorticoid treatment. Inflammopharmacology, 24(6), 397-402. http://doi.org/10.1007/s10787-016-0284-1

Grossman, J. M., Gordon, R., Ranganath, V. K., Deal, C., Caplan, L., Chen, W., Curtis, J., R., Furst, D. E., McMahon, M., Patkar, N. M., Volkmann, E., Saag, K. G. (2010). American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis. Arthritis Care Res (Hoboken), 62(11), 1515-1526. http://doi.org/10.1002/acr.20295

Hoes, J. N., van der Goes, M. C., Jacobs, J. W., Lafeber, F. P., Bijlsma, J. W. y Van Roon, J. A. (2011). Changes in macrophage inhibitory factor correlate with changes in bone mineral density in glucocorticoid-treated patients with rheumatoid arthritis. Rheumatology (Oxford), 50(10), 1921-1924. http://doi.org/10.1093/rheumatology/ker268

Huscher, D., Thiele, K., Gromnica-Ihle, E., Hein, G., Demary, W., Dreher, R., Zink, A. y Buttgereit, F. (2009). Dose-related patterns of glucocorticoid-induced side effects. Ann Rheum Dis, 68(7), 1119-1124. http://doi.org/10.1136/ard.2008.092163

Muñetón-Pérez, P. (2009). Plantas medicinales: un complemento vital para la salud de los mexicanos. Entrevista con el Mtro. Erick Estrada Lugo. Revista Digital Universitaria, 10(9). https://www.revista.unam.mx/vol.10/num9/art58/art58.pdf

Naranjo, A., Sokka, T., Descalzo, M. A., Calvo-Alen, J., Horslev-Petersen, K., Luukkainen, R. K., Bernard Combe, B., Burmester, G. R., Devlin, J., Ferraccioli, G., Morelli, A., Hoekstra, M., Majdan, M., Sadkiewicz, S., Belmonte, M., Holmqvist, A.-C., Choy, E., Tunc, R., Dimic, A., … The QUEST-RA Group (2008). Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Res Ther, 10(2), R30. http://doi.org/10.1186/ar2383

Park, Y. B., Ahn, C. W., Choi, H. K., Lee, S. H., In, B. H., Lee, H. C., Nam, C. M. y Soo-Kon Lee (2002). Atherosclerosis in rheumatoid arthritis: morphologic evidence obtained by carotid ultrasound. Arthritis Rheum, 46(7), 1714-1719. http://doi.org/10.1002/art.10359

Reichardt, S. D., Amouret, A., Muzzi, C., Vettorazzi, S., Tuckermann, J. P., Luhder, F. y Reichardt, H. M. (2021). The Role of Glucocorticoids in Inflammatory Diseases. Cells, 10(11). http://doi.org/10.3390/cells10112921

Shrestha, A. B., Aryal, M., Magar, J. R., Shrestha, S., Hossainy, L. y Rimti, F. H. (2022). The scenario of self-medication practices during the COVID-19 pandemic; a systematic review. Ann Med Surg (Lond), 82, 104482. http://doi.org/10.1016/j.amsu.2022.104482

Timmermans, S., Souffriau, J. y Libert, C. (2019). A General Introduction to Glucocorticoid Biology. Front Immunol, 10, 1545. http://doi.org/10.3389/fimmu.2019.01545

Weinstein, R. S. (2011). Clinical practice. Glucocorticoid-induced bone disease. N Engl J Med, 365(1), 62-70. http://doi.org/10.1056/NEJMcp1012926

Weinstein, R. S., Nicholas, R. W. y Manolagas, S. C. (2000). Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip. J Clin Endocrinol Metab, 85(8), 2907-2912. http://doi.org/10.1210/jcem.85.8.6714

Wilson, J. C., Sarsour, K., Gale, S., Petho-Schramm, A., Jick, S. S. y Meier, C. R. (2019). Incidence and Risk of Glucocorticoid-Associated Adverse Effects in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken), 71(4), 498-511. http://doi.org/10.1002/acr.23611

Los medicamentos no son dulces: empleo de glucocorticoides para enfermedades crónicas

Published

2024-02-27

Issue

Section

Artículos

How to Cite

Medications are not candies: use of glucocorticoids for chronic diseases. (2024). Inventio, 19(48), 1-9. https://doi.org/10.30973/inventio/2023.19.48/6

Most read articles by the same author(s)