Mitochondrial acetylation: the new frontier in cancer research
DOI:
https://doi.org/10.30973/inventio/2023.19.47/8Keywords:
mitochondrion, acetylation, post-translational modification, cancer, biomedicineAbstract
Cancer is a health problem that affects millions of people around the world. Being such a complex disease, not all aspects involved in its development are yet known. One of the cellular mechanisms that have attracted the interest of researchers is acetylation of proteins. This consists of adding acetyl groups to the amino acid chain of proteins. In mitochondrial proteins, this modification has a negative effect leading to impaired mitochondrial function, which induces changes in the cellular machinery that predispose to the onset and development of cancer. Modulation of mitochondrial protein acetylation patterns may be a viable therapeutic approach for the treatment of this disease.
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Copyright (c) 2005 Diana Lashidua Fernández Coto, Marisol Ayala Reyes
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Esta revista proporciona acceso abierto inmediato a su contenido, con base en el principio de ofrecer al público un acceso libre a las investigaciones para contribuir a un mayor intercambio global de conocimientos. Se distribuye bajo una licencia Creative Commons Reconocimiento-NoComercial 4.0 Internacional License.
