Biological chirality: the functional asymmetry of life
DOI:
https://doi.org/10.30973/inventio/2022.18.45/3Keywords:
chirality, biological information, dynamical systems, main tenet of molecular biologyAbstract
Chirality is a geometric property in objects that exist in two versions oriented in space as a reflection. The typical case is the hands, since the reflection of the left hand results in a right hand, and vice versa. In chemistry, reactions that generate chiral compounds do so in equivalent amounts of left and right molecules. In living systems, during protein synthesis, the cellular machinery only uses left amino acids, while the main metabolic pathways favor the use of right carbohydrates. In this paper we address the concept of chirality and show the evidence to consider it a characteristic that optimizes the flow of information in living systems.
References
Barron, L. D. (2013). True and false chirality and absolute enantioselection. Rend. Fis. Acc. Lincei, 24(3), 179-189. https://link.springer.com/content/pdf/10.1007/s12210-013-0224-6.pdf
Blum, M., Feistel, K., Thumberger, T. y Schweickert, A. (2014). The evolution and conservation of left-right patterning mechanisms. Development, 141(8), 1603-1613. https://doi.org/10.1242/dev.100560
Buhse, T., Cruz, J. M., Noble-Teran, M. E., Hochberg, D., Ribó, J. M., Crusats, J. y Micheau, J. C. (2021). Spontaneous deracemizations. Chemical Reviews, 121(4), 2147-2229. https://doi.org/10.1021/acs.chemrev.0c00819
Carroll, J. D. (2009). A new definition of life. Chirality, 21(3), 354-358. https://doi.org/10.1002/chir.20590
Clark, E. (2019). Pioneers in Optics: Jean-Baptiste Biot. Microscopy Today, 27(2), 40-41. https://doi.org/10.1017/S1551929519000014
Crick, F. (1970). Central dogma of molecular biology. Nature, 227(5258), 561-563. https://doi.org/10.1038/227561a0
Cronin, J. y Reisse, J. (2005). Chirality and the origin of homochirality. En Lectures in astrobiology (pp. 473-515). Springer, Berlin, Heidelberg. https://link.springer.com/content/pdf/10.1007%2F10913406_14.pdf
Cruz-Rosas, H. I., Riquelme, F., Ramírez-Padrón, A., Buhse, T., Cocho, G. y Miramontes, P. (2020). Molecular shape as a key source of prebiotic information. J Theor Biol, 499, 110316. https://doi.org/10.1016/j.jtbi.2020.110316
Inaki, M, Liu J y Matsuno, K. (2016). Cell chirality: its origin and roles in left –right asymmetric development. Phil Trans R Soc B, 371 (20150403). http://dx.doi.org/10.1098/rstb.2015.0403
Pinilla R. 1980. Pasteur. En: Genios y lideres de la historia, tomo XI, pp. 11-125. Ed. Promexa. México.
Shannon, C. E. (1948). A mathematical theory of communication. Bell Labs Tech J, 27(3), 379-423. https://doi.org/10.1002/j.1538-7305.1948.tb01338.x
Varela, F. G., Maturana, H. R. y Uribe, R. (1974). Autopoiesis: The organization of living systems, its characterization and a model. Biosystems, 5(4), 187-196. https://doi.org/10.1016/0303-2647(74)90031-8
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Copyright (c) 2005 Hugo Iván Cruz Rosas, María Eugenia Noble Terán, José Manuel Cruz, Thomas Buhse

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